{"product_id":"mots-c-20mg-1","title":"MOTS-C 20mg Per Vial","description":"\u003cdiv style=\"background-color: #1a2744; border-radius: 8px; padding: 16px 20px; margin-bottom: 16px; display: flex; align-items: center; gap: 14px;\"\u003e\n\u003cspan style=\"font-size: 24px; color: #ffffff;\"\u003e✔\u003c\/span\u003e\n\u003cdiv\u003e\n\u003cp style=\"margin: 0; color: #ffffff; font-weight: bold; font-size: 15px;\"\u003eBacteriostatic (BAC) Water Included\u003c\/p\u003e\n\u003cp style=\"margin: 4px 0 0; color: #c8d0e0; font-size: 13px;\"\u003eNo separate purchase required\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"display: flex; flex-wrap: wrap; gap: 8px; margin-bottom: 16px; justify-content: center;\"\u003e\n\u003cspan style=\"background-color: #eef1f7; color: #1a2744; font-size: 12px; font-weight: 600; padding: 5px 12px; border-radius: 20px; letter-spacing: 0.03em;\"\u003eMitochondrial Support\u003c\/span\u003e \u003cspan style=\"background-color: #eef1f7; color: #1a2744; font-size: 12px; font-weight: 600; padding: 5px 12px; border-radius: 20px; letter-spacing: 0.03em;\"\u003eMetabolic Research\u003c\/span\u003e \u003cspan style=\"background-color: #eef1f7; color: #1a2744; font-size: 12px; font-weight: 600; padding: 5px 12px; border-radius: 20px; letter-spacing: 0.03em;\"\u003eCellular Energy\u003c\/span\u003e\n\u003c\/div\u003e\n\u003chr\u003e\n\u003cdiv style=\"background-color: #f0f3f8; border-left: 4px solid #1a2744; border-radius: 4px; padding: 14px 18px; margin-bottom: 16px;\"\u003e\n\u003cp style=\"margin: 0; color: #1a2744; font-style: italic; font-size: 15px;\"\u003eMOTS-C is one of the few peptides encoded directly by mitochondrial DNA - placing it at a unique intersection of energy biology, metabolic research and longevity science.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch4\u003e\u003cstrong\u003eWhat is MOTS-C?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eMOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring 16-amino-acid mitochondrial-derived peptide that has become an exciting area of research into cellular energy regulation, metabolic health, exercise adaptation and mitochondrial function.\u003c\/p\u003e\n\u003cp\u003eUnlike many peptides that originate from nuclear DNA, MOTS-C is encoded within the mitochondrial genome itself. Research suggests that it acts as a signalling molecule between mitochondria and the rest of the cell, helping researchers better understand how the body responds to changes in energy demand, exercise and metabolic stress.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eWhy is MOTS-C interesting?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eMitochondria are often described as the “powerhouses” of the cell because they are responsible for producing much of the energy cells need to function. MOTS-C is being investigated for its potential role in regulating the way cells respond to energy demands and metabolic stress.\u003c\/p\u003e\n\u003cp\u003eOne of the key pathways associated with MOTS-C is AMPK, an important cellular energy-sensing pathway. AMPK helps cells respond when energy requirements increase and plays a central role in glucose and energy metabolism. Research has shown that MOTS-C can influence AMPK-related signalling and metabolic pathways, particularly in skeletal muscle.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eMOTS-C \u0026amp; Metabolic Research\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eEarly research has identified MOTS-C as a potentially important regulator of metabolic homeostasis. In preclinical research, MOTS-C administration has been associated with improved insulin sensitivity and protection against diet-induced metabolic changes.\u003c\/p\u003e\n\u003cp\u003eHuman research has also investigated naturally circulating MOTS-C levels in relation to insulin sensitivity and metabolic status. These studies help researchers understand the peptide’s biological role, although they do not establish MOTS-C as a treatment for diabetes, obesity or other medical conditions.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eMOTS-C \u0026amp; Mitochondrial Function\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eOne of the most interesting areas of current MOTS-C research is its relationship with mitochondrial performance and cellular energy production.\u003c\/p\u003e\n\u003cp\u003eRecent research found that MOTS-C can improve aspects of skeletal-muscle mitochondrial bioenergetic function in animal models through pathways involving AMPK and PGC-1α, while also reducing markers associated with mitochondrial oxidative stress.\u003c\/p\u003e\n\u003cp\u003eThis makes MOTS-C particularly interesting for researchers studying the connection between mitochondrial efficiency, cellular energy production and metabolic adaptation.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eMOTS-C \u0026amp; Exercise Research\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eMOTS-C is also being studied in connection with exercise and physical performance. Research has found relationships between MOTS-C, exercise-induced metabolic signalling and mitochondrial adaptations. Studies have investigated its role in exercise capacity, skeletal-muscle metabolism and the body’s response to increased energy demand.\u003c\/p\u003e\n\u003cp\u003eAnimal research has further explored MOTS-C in relation to physical performance and age-related changes in muscle function.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eMOTS-C \u0026amp; Muscle Research\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eAnother emerging area of interest is skeletal-muscle health. Research has investigated MOTS-C in relation to pathways involved in muscle metabolism, muscle maintenance and muscle atrophy. More recent laboratory research using human skeletal-muscle cells found that MOTS-C helped preserve certain measures of muscle-cell structure under experimentally induced atrophy conditions.\u003c\/p\u003e\n\u003cp\u003eThese findings are promising for further research into how mitochondrial signalling may influence muscle and metabolic function, but additional human clinical research is required.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eWhat makes MOTS-C different?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial function\u003c\/strong\u003e — Research into how cells produce and utilise energy.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAMPK signalling\u003c\/strong\u003e — Investigation into one of the body’s major cellular energy-sensing pathways.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucose \u0026amp; metabolic pathways\u003c\/strong\u003e — Research into how cells respond to changes in glucose and energy availability.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExercise adaptation\u003c\/strong\u003e — Investigation into mitochondrial and metabolic responses to physical activity.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkeletal-muscle research\u003c\/strong\u003e — Exploration of cellular pathways involved in muscle metabolism and maintenance.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular stress response\u003c\/strong\u003e — Research into how cells adapt to metabolic and oxidative stress.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eA peptide at the forefront of mitochondrial research\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eMOTS-C represents a relatively new area of peptide science, with researchers continuing to investigate how mitochondria communicate with cells and influence whole-body metabolism. While much of the exciting evidence surrounding MOTS-C remains preclinical or mechanistic, the growing body of research has made it an important peptide for investigating mitochondrial signalling, metabolic regulation and cellular energy homeostasis.\u003c\/p\u003e\n\u003cp\u003ePeptigen MOTS-C 20 mg is supplied strictly for laboratory research purposes.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch4\u003e\u003cstrong\u003eResearch Areas at a Glance\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eMitochondrial Function • Cellular Energy • AMPK Signalling • Metabolic Research • Exercise Adaptation • Skeletal Muscle Research • Cellular Stress Response\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003csmall\u003eResearch Disclaimer: MOTS-C is an investigational research compound and is not currently approved by SAHPRA, the FDA, or other major regulatory authorities for therapeutic or consumer applications. Peptigen products are provided exclusively for laboratory research. Information on this website is presented for general scientific and educational purposes and should not be considered medical advice, a treatment recommendation, or guidance for personal use. Peptigen does not provide dosing, administration or reconstitution guidance for research compounds. Purchasers are responsible for ensuring that research materials are handled within an appropriate research environment and in accordance with relevant laws, regulations, laboratory protocols and safety requirements. Research use only.\u003c\/small\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePeptigen.\u003c\/strong\u003e\u003cbr\u003eQuality. Research. Potential.\u003c\/p\u003e","brand":"Peptigen","offers":[{"title":"Default Title","offer_id":48650482843889,"sku":null,"price":850.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0807\/3982\/7953\/files\/MOTS-C20MG.jpg?v=1787912893","url":"https:\/\/peptigen.co.za\/products\/mots-c-20mg-1","provider":"PEPTIGEN","version":"1.0","type":"link"}