{"product_id":"reta-30mg-per-vial","title":"RETA (GLP-3) 30mg Per Vial","description":"\u003cdiv style=\"background-color: #1a2744; border-radius: 8px; padding: 16px 20px; margin-bottom: 16px; display: flex; align-items: center; gap: 14px;\"\u003e\n\u003cspan style=\"font-size: 24px; color: #ffffff;\"\u003e✔\u003c\/span\u003e\n\u003cdiv\u003e\n\u003cp style=\"margin: 0; color: #ffffff; font-weight: bold; font-size: 15px;\"\u003eBacteriostatic (BAC) Water Included\u003c\/p\u003e\n\u003cp style=\"margin: 4px 0 0; color: #c8d0e0; font-size: 13px;\"\u003eNo separate purchase required\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"display: flex; flex-wrap: wrap; gap: 8px; margin-bottom: 16px; justify-content: center;\"\u003e\u003cspan style=\"background-color: #eef1f7; color: #1a2744; font-size: 12px; font-weight: 600; padding: 5px 12px; border-radius: 20px; letter-spacing: 0.03em;\"\u003eTriple-Receptor Metabolic Research\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv style=\"display: flex; flex-wrap: wrap; gap: 8px; margin-bottom: 16px; justify-content: center;\"\u003e\n\u003cspan style=\"background-color: #eef1f7; color: #1a2744; font-size: 12px; font-weight: 600; padding: 5px 12px; border-radius: 20px; letter-spacing: 0.03em;\"\u003eGLP-1\u003c\/span\u003e\u003cspan style=\"background-color: #eef1f7; color: #1a2744; font-size: 12px; font-weight: 600; padding: 5px 12px; border-radius: 20px; letter-spacing: 0.03em;\"\u003e\u003cspan style=\"letter-spacing: 0.03em;\"\u003eGIP\u003c\/span\u003e\u003c\/span\u003e \u003cspan style=\"background-color: #eef1f7; color: #1a2744; font-size: 12px; font-weight: 600; padding: 5px 12px; border-radius: 20px; letter-spacing: 0.03em;\"\u003e\u003cspan style=\"letter-spacing: 0.03em;\"\u003eGLUCAGON\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003chr\u003e\n\u003cdiv style=\"background-color: #f0f3f8; border-left: 4px solid #1a2744; border-radius: 4px; padding: 14px 18px; margin-bottom: 16px;\"\u003e\n\u003cp style=\"margin: 0; color: #1a2744; font-style: italic; font-size: 15px;\"\u003eRETA is one of the few investigational compounds targeting three major metabolic receptors simultaneously - making it a uniquely powerful model for energy-balance research.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch4\u003e\u003cstrong\u003eWhat is RETA (GLP-3)?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eRETA (GLP-3) is an investigational metabolic peptide being studied for its activity across three important hormonal pathways: GLP-1, GIP and glucagon receptors. This combination has made RETA an exciting area of current metabolic research, particularly in relation to energy balance, glucose regulation, appetite signalling and body composition.\u003c\/p\u003e\n\u003cp\u003eUnlike compounds that act primarily through a single metabolic pathway, RETA allows researchers to investigate the interaction between three complementary signalling systems within one molecule.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eWhy is RETA interesting?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eThe three pathways targeted by RETA each have important roles in human metabolism.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGLP-1\u003c\/strong\u003e is involved in glucose-dependent insulin secretion, appetite signalling and gastrointestinal regulation.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGIP\u003c\/strong\u003e is an incretin hormone involved in nutrient sensing and insulin secretion and is increasingly being studied for its broader metabolic effects.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucagon\u003c\/strong\u003e plays an important role in hepatic metabolism, energy mobilisation and the body’s response to changing energy demands.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe combination of these pathways is what makes RETA particularly interesting to researchers investigating metabolic regulation.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eRETA \u0026amp; GLP-1 Signalling\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eGLP-1 is naturally released in response to food intake and plays an important role in glucose homeostasis. GLP-1 receptor signalling influences glucose-dependent insulin secretion, glucagon regulation, gastrointestinal activity and appetite-related pathways. RETA provides researchers with an opportunity to investigate GLP-1 activity alongside GIP and glucagon signalling rather than studying these pathways independently.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eRETA \u0026amp; GIP Signalling\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eGIP, or glucose-dependent insulinotropic polypeptide, is another naturally occurring incretin hormone. GIP responds to nutrient intake and contributes to glucose-dependent insulin secretion. Researchers are increasingly interested in how GIP signalling interacts with GLP-1 signalling and how these pathways may complement one another.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eRETA \u0026amp; Glucagon\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eGlucagon is an important regulator of energy availability and hepatic metabolism. It influences processes involved in mobilising stored energy and regulating substrate utilisation. The addition of glucagon receptor activity creates an interesting research model for investigating the relationship between energy expenditure, fuel utilisation and incretin signalling.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eRETA \u0026amp; Metabolic Research\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eRETA has progressed into advanced clinical research, with Phase 3 studies investigating its effects in obesity and related metabolic conditions. Recent Phase 3 results have reported substantial changes in body weight and glycaemic measures in studied populations, while the compound remains investigational and is not yet approved for public use.\u003c\/p\u003e\n\u003cp\u003eThese findings have increased interest in RETA’s unique triple-receptor mechanism and its potential role in future metabolic research.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eWhat makes RETA different?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple-receptor activity\u003c\/strong\u003e — Research into GLP-1, GIP and glucagon signalling simultaneously.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic signalling\u003c\/strong\u003e — Investigation into several interconnected pathways involved in energy regulation.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAppetite research\u003c\/strong\u003e — Study of hormonal pathways involved in food intake and satiety.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy-balance research\u003c\/strong\u003e — Investigation into the relationship between energy intake, expenditure and substrate utilisation.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBody-composition research\u003c\/strong\u003e — Study of changes in body weight and metabolic parameters.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eA new direction in metabolic research\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eRETA represents an exciting direction in metabolic science because it brings together three major hormonal pathways within a single investigational molecule. The research continues to develop, with ongoing studies examining its longer-term effects, safety profile and potential applications.\u003c\/p\u003e\n\u003chr\u003e\n\u003ch4\u003e\u003cstrong\u003eResearch Areas at a Glance\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eGLP-1 Signalling • GIP Signalling • Glucagon Receptor • Metabolic Regulation • Appetite Research • Energy Balance • Body Composition\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003csmall\u003eResearch Disclaimer: RETA is an investigational compound intended for scientific research and is not currently approved by SAHPRA, the FDA, or other major regulatory authorities for therapeutic or consumer applications. Peptigen products are provided exclusively for laboratory research. Information on this website is presented for general scientific and educational purposes and should not be considered medical advice, a treatment recommendation, or guidance for personal use. Peptigen does not provide dosing, administration or reconstitution guidance for research compounds. Purchasers are responsible for ensuring that research materials are handled within an appropriate research environment and in accordance with relevant laws, regulations, laboratory protocols and safety requirements. Research use only.\u003c\/small\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePeptigen.\u003c\/strong\u003e\u003cbr\u003eQuality. Research. Potential.\u003c\/p\u003e","brand":"PEPTIGEN","offers":[{"title":"Default Title","offer_id":48418430484721,"sku":null,"price":1550.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0807\/3982\/7953\/files\/RETA.jpg?v=1787913316","url":"https:\/\/peptigen.co.za\/products\/reta-30mg-per-vial","provider":"PEPTIGEN","version":"1.0","type":"link"}