PT-141 10mg Per Vial

What is PT-141?

PT-141, also known as bremelanotide, is a synthetic melanocortin-related peptide that has been investigated primarily for its effects on central melanocortin signalling, sexual motivation and sexual-function pathways. Its mechanism makes it particularly interesting because it acts through central melanocortin pathways rather than functioning primarily through traditional peripheral vascular mechanisms.

Why is PT-141 interesting?

PT-141 is related to α-MSH and acts on melanocortin receptors, with particular interest surrounding MC4R signalling. Melanocortin receptors are involved in several physiological processes, including energy balance and sexual behaviour.

PT-141 & Sexual-Function Research

One of the most significant areas of research surrounding PT-141 has involved sexual desire and arousal. Research suggests that melanocortin signalling within the central nervous system can influence neural pathways involved in sexual motivation.

PT-141 & the Brain

Unlike many compounds investigated for sexual function, PT-141’s research profile is particularly focused on central nervous-system signalling. Researchers have investigated interactions between melanocortin pathways and neurotransmitter systems involved in motivation and behaviour.

PT-141 & Melanocortin Receptors

The melanocortin receptor family contains several receptor subtypes with different biological roles. PT-141 provides researchers with an opportunity to study the relationship between melanocortin receptor activation and:

• Sexual motivation
• Neuroendocrine signalling
• Central nervous-system pathways
• Energy balance
• Behavioural responses

Clinical Research

Bremelanotide has been studied in human clinical trials and has an FDA-approved pharmaceutical indication for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD). The FDA specifically states that the approved product is not indicated to enhance sexual performance.

Research Areas at a Glance

Melanocortin Biology • MC4R Signalling • Sexual Motivation • Neuroendocrine Research • Central Nervous System • Behavioural Biology • Sexual-Function Research

Research Disclaimer: PT-141/bremelanotide has an approved pharmaceutical application in a specific jurisdiction and indication; however, the Peptigen product is supplied exclusively for laboratory research purposes. Information provided on this website is intended for scientific and educational purposes and should not be considered medical advice, a treatment recommendation, or guidance for personal use. Peptigen does not provide dosing, administration or reconstitution guidance for research compounds. Purchasers are responsible for ensuring that research materials are handled within an appropriate research environment and in accordance with applicable laws, regulations, laboratory protocols and safety requirements. Research use only.

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