PT-141 10mg Per Vial

◆ Price includes BAC Water (Bacteriostatic Water) — ready for reconstitution

PT-141 10mg

PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist derived from the peptide Melanotan II. Unlike many compounds studied in sexual health research, PT-141 acts centrally via the melanocortin system rather than through vascular mechanisms, making it a unique subject in neuroendocrine and behavioural research.

Key Research Areas

1. Melanocortin Receptor Activation

PT-141 acts as an agonist at MC3R and MC4R (melanocortin 3 and 4 receptors) in the central nervous system, pathways involved in sexual arousal, appetite regulation, and energy homeostasis.

2. Sexual Function Research

PT-141 has been extensively studied in models of sexual dysfunction, with research exploring its central nervous system-mediated effects on arousal and desire in both male and female models.

3. Appetite and Energy Regulation

Through MC4R activation, PT-141 is also studied in the context of appetite suppression and energy balance, overlapping with broader melanocortin system research.

4. Neuroendocrine Modulation

Research has explored PT-141’s broader effects on the hypothalamic-pituitary axis and its interactions with other neuroendocrine pathways regulated by the melanocortin system.

Why PT-141 is Studied

• Central melanocortin receptor (MC3R/MC4R) agonism
• CNS-mediated mechanism distinct from vascular approaches
• Sexual function and arousal research models
• Appetite regulation and energy homeostasis
• Neuroendocrine and hypothalamic pathway modulation

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